Section 1 of Part 2: How Could A Gluten Intolerance Cause Amyotrophic Lateral Sclerosis (ALS) Or Lou Gehrig’s Disease?

March 9, 2011 · Filed Under ALS · 8 Comments 

This is part 2 of a 5 part series discussing how ALS could be caused by a gluten intolerance, other types of allergies, and/or by a reaction to lectins. In this part of the series, the possible association between ALS and a gluten intolerance is discussed. Due to the length of this part, I will need to break it into 8 posts/sections. At the end of this post, I have outlined the series for you. Today, section one will discuss how reactions against transglutaminases may contribute to symptoms.

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Part 1 Of 5 Part Series: Could A Gluten Intolerance Cause Amyotrophic Lateral Sclerosis (ALS) Or Lou Gehrig’s Disease?

February 17, 2011 · Filed Under ALS · 20 Comments 

I would like to dedicate this series of posts to my grandfather, Jack, who died from amyotrophic lateral sclerosis (ALS) when I was in my early teens. He was a tall thin man who was always smiling and maintained a positive outlook even in the midst of ill health. His daughter (my mother), my daughter and I all have celiac disease (one type of gluten intolerance). I have to wonder whether his symptoms were really associated with a gluten intolerance. Over the past six years, I have come across a great deal of research linking neurological symptoms to immune reactions to gluten. This peaked my curiosity. Did the ingestion of gluten trigger a cascade of immune reactions, eventually leading to the development of ALS in my grandfather. This is an intriguing question and I believe the connection is very possible. With all forms of gluten intolerance, it seems very plausible that autoimmune factors (anti-neuro antibodies), inflammation, and malabsorption of nutrients could lead to the neurological symptoms associated with ALS.

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