Section 3 of Part 2: Could Glutamic Acid And Aspartic Acid Contribute To Amyotrophic Lateral Sclerosis (ALS) Or Lou Gehrig’s Disease?
According to John B. Symes, D.V.M., wheat, dairy, and soy contain high levels of glutamic acid and aspartic acid. High levels of these two non-essential amino acids can over activate the receptors of the nerve cells and lead to excitotoxicity and neurological damage in animals. Dr. Symes’s research suggests that this can lead to nerve and brain impairments which are evident in many neurodegenerative diseases. Possibly, his findings could be applicable to humans.
With Dr. Symes’s theory in mind, further research may find that people with ALS have a sensitivity to the glutamic acid and aspartic acids in certain foods, like wheat, diary and soy. Dr. Symes suggests that the ingestion of foods with high levels may overload the neurological system and have toxic effects. If his theory proves true, I wonder if this could lead to ALS symptoms. This is just one more possibility for people with ALS to consider.
Keep in mind that this is a hypothetical theory that John B. Smymes has suggested and it should be discussed with your doctor before you make any dietary changes. With this series, I am trying to think outside of the box and present many different ideas for people to think about and discuss with their doctor.
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The rest of Part 2, along with parts, 3, 4, and 5 will follow in the next 2-3 months.
5 Part Series
Part 2 Of 5 Part ALS Series: How Could A Gluten Intolerance Cause Amyotrophic Lateral Sclerosis (ALS) Or Lou Gehrig’s Disease? (see 8 sections of Part 2 below)
Section 3 of Part 2: Could Glutamic Acid And Aspartic Acid Contribute To ALS Symptoms
Section 4 of Part 2: Abnormal Neurological Findings With A Gluten Intolerance
Section 5 of Part 2: Can Nutrient Deficiencies Contribute And How is This Associated With A Gluten intolerance?
Section 6 of Part 2: Are There studies Showing An Association Between Gluten And ALS?
Part 3 Of 5 Part Series: How Could A Gluten Intolerance Cause ALS In Various Age Groups
Part 4 Of 5 Part Series: How could A Lectin Intolerance Contribute To ALS
Part 5 Of 5 Part Series: Some Final Thoughts About ALS And Gluten
If you have difficulty with any of the above links, scroll down the right side of my blog until you find ALS. All of the ALS posts will be found in this category.
1. Hynd MR, Scott HL, Dodd PR. Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer’s disease. Neurochem Int. 2004 Oct;45(5):583-95.
2. Manev H, Favaron M, Guidotti A, Costa E (July 1989). "Delayed increase of Ca2+ influx elicited by glutamate: role in neuronal death". Mol. Pharmacol. 36 (1): 106–12.
3. Smith QR (April 2000). "Transport of glutamate and other amino acids at the blood-brain barrier". J. Nutr. 130 (4S Suppl): 1016S–22S.
4. Website: dogtorj.com
5. Adam Doble. The Role of Excitotoxicity in Neurodegenerative Disease: Implications for Therapy. Pharmacology & Therapeutics Volume 81, Issue 3, March 1999, Pages 163-221
6. Christopher G. Goetz. Excitotoxins and Excitotoxicity. Rush-Presbyterian-St. Luke’s Medical Center, USA