Could Tissue Transglutaminase Be The Autoantigen In Most Diseases And How Could This Be Related To A Gluten Intolerance?
Transglutaminases are very important enzymes. These enzymes are involved in many functions, such as tissue repair, signalling processes, cellular differentiation (cells become more specialized), matrix stabilization (tissue that provides support to cells), and apoptosis (biochemical change that causes death in cells that are not needed). Without it, tissue repair is hindered, unfavourable cellular changes can occur, abnormal cells could grow uncontrollably leading to cancer and signalling between cells could be affected. These changes could occur in any area of the body where the enzyme is not available.